Check out a couple of blog posts from Hugh 'Ignore Everybody' Macleod. The first is about how Hugh feels great examples start off with something futile. He lists a bunch of things he's achieved and some campaigns he admires too.
In an earlier post he explains a bit more about his Blue Monster idea, focusing on the Microsoft employee who loved it so much he got it tattooed on his arm, but then was laid off. Read the full post it makes out there's a happy ending in there (we all love happy endings).